Leadership

Directors - Core Research Areas

  • Ian Corbin, Ph.D.

    ASSOCIATE PROFESSOR
    DIRECTOR Translational Nanomedicine & Drug Delivery
    Research Interests: Nanomedicine and image-guided drug delivery for novel diagnostic and therapeutic applications in oncology
    Corbin Lab

  • Gaudenz Danuser, Ph.D.

    PROFESSOR
    DIRECTOR Computational Biology
    LYDA HILL DEPARTMENT OF BIOINFORMATICS CHAIR
    Research interests: Causal inference in molecular pathways, cell morphological control of signaling and metabolism, computer vision and machine learning of cell dynamics, roles and regulation of cell morphogenesis in metastasis, especially in pediatric sarcomas
    Danuser Lab

  • Yasin Dhaher, Ph.D.

    PROFESSOR
    DIRECTOR Biomaterials, Mechanics, and Tissue Engineering
    Research Interests: Understand the basic biomechanical and neurophysiological properties of the lower limb after neurological lesions. Explore the neuro-mechanical underpinnings of lower limb impairments after stroke, with the goal of informing future clinical interventions

  • Anke Henning, Ph.D.

    PROFESSOR
    DIRECTOR Biomedical & Molecular Imaging
    Advanced Imaging Research Center
    Research Interests: Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; ultra-high field MRI; hardware; RF coils; B0 shimming; sequence development; data analysis
    AIRT Lab

  • You Zhang, Ph.D.

    ASSISTANT PROFESSOR
    DIRECTOR Medical Physics
    Research Interests: 3D/4D CT/CBCT reconstruction and analysis, 4D MRI reconstruction, artificial intelligence and automation in radiation therapy, biomechanical modeling and finite element analysis, deformable registration and its application in image-guided radiation therapy, radiotherapy dose calculation and plan optimization
    AIRT Lab

Faculty

  • Asaithamby Aroumougame, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Immunotherapy and radiotherapy in cancer prevention and treatment; premature aging and carcinogenesis; DNA damage response signaling in heart development

  • Spencer Bowen, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Development of hybrid positron emission tomography (PET) (e.g. PET-CT and PET-MR) tools to enable precision imaging for the care and study of oncology, neurology, and cardiology patients

  • Shawn Burgess, Ph.D.

    PROFESSOR
    Research Interests: NMR spectroscopy and mass spectroscopy in conjunction with the application of stable isotope tracers to study metabolic function

  • David Busch, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Developing non- and minimally invasive optical tools to monitor deep tissues in health and disease, as well as throughout therapy

  • Thomas Carroll, Ph.D.

    PROFESSOR
    Research Interests: Cancer, cell polarity, developmental biology, morphogenesis, stem/progenitor cells, tissue engineering and regeneration.

  • Maria Chahrour, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Genomic, genetic, and molecular approaches to autism spectrum disorders

  • Jonathan Cheng, M.D.

    PROFESSOR
    Research Interests: Nerve regeneration; long nerve gap repair; nerve-machine interface

  • Ian Corbin, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests:
    Molecular imaging techniques and nanomedicine-technology development to better understand and characterize liver disease

  • Lindsay Cowell, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Somatic diversification of antigen receptor genes; repertoire characteristics as biomarkers of immune status and disease; host-pathogen interactions

  • Kevin Dean, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Metastatic colonization, autonomous light-sheet microscopy, optical probes, computer vision

  • Caroline de Gracia Lux, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Ultrasound contrast agent, perfluorocarbon emulsions, development of new ultrasound-based strategies for early detection and treatment of diseases

  • Reto Fiolka, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: The long-term goal of our lab’s research is to develop and implement imaging technologies that provide unprecedented insight into cancer biology

  • Thomas Floyd, M.D.

    PROFESSOR
    Research Interests: Prevention and early detection of neurological injury associated with surgery

  • Jinming Gao, Ph.D.

    PROFESSOR
    Research Interests: Activatable optical/MRI imaging probes to study tumor metabolism and theranostic nanomedicine for cancer-targeted drug therapy

  • Gerald Greil, M.D., Ph.D.

    PROFESSOR
    Research interests: Evaluate the use of newly designed biodegradable stints to treat pulmonary artery stenosis

  • Nick Grishin, Ph.D.

    PROFESSOR
    Research Interests: Computational biology; analysis of protein sequences and structures

  • Daniel Heitjan, Ph.D.

    PROFESSOR
    CHAIR, Statistical Science at SMU

  • Gary Hon, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Single-cell regulatory genomics, cell fate engineering, function of non-coding elements and genetic variants.

  • Connie Hsia, M.D.

    PROFESSOR
    Research Interests: Heart-lung interaction; lung morphometry; structure-function correlation of lung growth

  • Mohammad Hussain (M. Tarique Hussain), M.D., Ph.D.

    PROFESSOR
    Research interests: Assessment of ventriculographie-arterial coupling in congenital and acquired heart disease. Cardiac MRI for improved vascular imaging

  • Khuloud Jaqaman, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Quantitative single-molecule imaging of receptor organization and signaling; linking molecular and cellular behavior across multiple scales; computational image analysis and data multiplexing

  • Steve Jiang, Ph.D.

    VICE CHAIR & CHIEF, PROFESSOR
    Research Interests: Cloud and GPU-based high-performance computing in medical physics and imaging; automatic radiotherapy treatment planning; adaptive radiotherapy; image-guided radiotherapy; low-dose and dynamic-cone-beam CT

  • Lukasz Joachimiak, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Molecular recognition in protein folding, chaperone structural biology and neurodegeneration

  • Daehwan Kim, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: DNA, RNA, and bisulfite sequence alignment, graph alignment to population of genomes and genotyping, personalized medicine with a focus on cancer diagnosis

  • Genevieve Konopka, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Comparative genomics, epigenetics, and alternative splicing analyses relevant to brain evolution and cognitive disorders

  • Zoltan Kovacs, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Generation and application of hyperpolarized13C-labeled compounds and89Y-complexes for MRI/ Radiopharmaceutical applications

  • William Lee Kraus, Ph.D.

    PROFESSOR & DIRECTOR
    Research Interests: Computational genomics. Using molecular, genetic, genomic, and computational approaches to understanding signal-regulated gene expression. Integrating data from different genomic platforms using computational approaches

  • Benjamin Levi, M.D.

    ASSOCIATE PROFESSOR & DIVISION CHIEF
    Research Interests: Cell fate, wound healing, muscle fibrosis, heterotopic ossification, injury response

  • Bo Li, Ph.D.

    ASSISTANT PROFESOR
    Research Interests: Computational cancer immunology, tumor-immune interaction and high-throughput profiling of immune receptor repertoire

  • Wen-Hong Li, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Probe engineering and targeted drug delivery to islet cells for treating diabetes; Islet biology with an emphasis on functional analysis on zinc signaling and zinc transporters in islet endocrine cells

  • Xiaochun Li, Ph.D.

    ASSOCIATE PROFESOR
    Research Interests: Structural and biochemical characterization of membrane proteins in cholesterol biosynthesis, metabolism and signaling

  • Milo Lin, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Theoretical and computational approaches to predict protein folding and aggregation; evolutionary dynamics

  • Jiaen Liu, PhD

    ASSISTANT PROFESSOR
    Research Interests: Fast and motion-robust MRI acquisition and reconstruction, high-resolution MRI for in vivo imaging intracortical structure and deep nuclei, & novel MRI contrast and quantification of tissue properties

  • Weiguo Lu, Ph.D.

    PROFESSOR
    Research Interests: Adaptive radiation therapy; treatment-plan optimization; radiation-dose calculations

  • Jacques Lux, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Bioresponsive nanomaterials for in vivo detection and therapy; targeted and activatable ultrasound (US) agents for the detection of inflammation and cancer

  • Ananth Madhuranthakam, Ph.D.

    DIRECTOR - MAGNETIC RESONANCE RESEARCH
    ASSOCIATE PROFESSOR
    Research Interests: Development and clinical translation of novel MR imaging techniques for detection and assessment of therapy response; non-contrast perfusion using arterial spin labeled (ASL) MRI; fat/water separated MRI; Whole-body MRI; MR Physics

  • Mala Mahendroo, Ph.D.

    PROFESSOR
    Research Interests: Parturition (the process of labor); cervical ripening; male and female reproductive biology

  • Joseph Maldijan, Ph.D.

    CHIEF - NEURORADIOLOGY
    PROFESSOR & DIVISION CHIEF

    Research Interests: Deep Learning applications in neuroimaging including brain tumor molecular marker prediction, Traumatic Brain Injury, MEG, MRI, fMRI

  • Craig Malloy, M.D.

    PROFESSOR
    Research Interests: 13C MRS methods for measuring cardiac intermediary-metabolism flux and function analysis/neurotransmitter metabolism of human brain

  • Ralph P. Mason, Ph.D., C.Sci, C.Chem

    DIRECTOR - PRE-CLINICAL IMAGING RESEARCH
    PROFESSOR

    Research Interests: Tumor pathophysiology and MR assessment of prognostic biomarkers/hypoxia and pH

  • Albert Montillo, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Developing state-of-the-art machine-learning approaches to extract radiological imaging and imaging-genomic biomarkers for individualized prognostics in neuroscience and oncological applications

  • Dan Nyugen, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Radiation therapy treatment planning, optimization techniques and algorithms, artificial intelligence technology development and applications

  • Zbyszek Otwinowski, Ph.D.

    PROFESSOR
    Research Interests: Methods development for cryo-electron microscopy, X-ray crystallography, and next-generation sequencing; Structural studies of macromolecules with X-ray crystallography and cryo-EM single particle reconstruction; Higher-order structure of eukaryotic chromatin.

  • Orhan Oz, M.D., Ph.D.

    PROFESSOR & DIVISION CHIEF
    MEDICAL DIRECTOR AT PARKLAND
    DIRECTOR - NUCLEAR MEDICINE RESIDENCY PROGRAM

    Research Interests: Application of structural (X-ray, CT, and MR) and functional (SPECT and PET) imaging methods to quantify changes in bone mass and metabolism induced by metabolic bone diseases; in vivo assessment of beta-cell mass and function by novel probes; novel PET and SPECT probe development for bone cells

  • Jae Mo Park, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Development of noninvasive molecular imaging tools to elucidate in vivo metabolism

  • Ivan Pedrosa, M.D., Ph.D.

    PROFESSOR & VP (Radiology Research)
    Research Interests: Development of novel MRI techniques for improved diagnosis of abdominal/pelvic diseases and noninvasive in vivo assessment of physiology and response to therapy in tumors

  • Matthias Peltz, M.D.

    ASSOCIATE PROFESSOR & SURGICAL DIRECTOR OF CARDIAC TRANSPLANT
    Research Interests: Heart, lung, and perfusion preservation, magnetic resonance spectroscopy

  • Satwik Rajaram, Ph.D.

    ASSISTANT PROFESOR
    Research Interests: Spatial organization of tumors by combining machine identified phenotypes and existing pathology scoring within the framework established by cancer biology

  • Kimberly Reynolds, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Molecular evolution, using protein sequence analysis to predict mutational effects on function, engineering protein regulation, mapping and modeling the relationship between enzyme activity and cellular growth rate, co-evolution in metabolic pathways.

  • Luke Rice, Ph.D.

    PROFESSOR
    Research Interests: Integrating structure, kinetics, and computation to understand the molecular determinants and regulatory mechanisms of microtubule dynamics

  • Elliot Ross, Ph.D.

    PROFESSOR & ASSOCIATE DEAN, Basic Research
    Research Interests: Cellular information processing; molecular mechanisms of G protein-mediated signaling: amplification, selectivity, response kinetics and signal integration

  • Debrata Saha, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Role of cycloxygenase-2 in radiation and chemo-resistance, role of small molecule inhibitors as radio-sensitizers

  • Daniel Siegwart, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Polymer and materials chemistry, drug and gene delivery, RNAi, biomedical imaging, detection and treatment of cancer

  • Baran Sumer, M.D.

    PROFESSOR
    Research Interests: Clinical application of nanoprobes with unique nanoscale behavior

  • Xiankai Sun, Ph.D.

    PROFESSOR
    DIRECTOR, Cyclotron & Radiochemistry Program
    Research Interests: Development of PET, SPECT, and MRI imaging probes to assess biological abnormalities and evaluation of disease treatment

  • Erdal Toprak, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Antibiotic resistance and sensitivity; single molecule biophysics; synthetic biology

  • Elena Vinogradov, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Endogenous and exogenous MRI contrast agents and mechanisms in vivo, CEST and PARACEST imaging, hyperpolarization

  • Jing Wang, Ph.D.

    ASSOCIATE PROFESSOR
    DIRECTOR, Data Analytics & Informatics
    Research Interests: Immunogenomics, Tumor genomics, Bioinformatics, Biostatistics, and Machine learning

  • Kang-Hsin Wang, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Biomedical optics, In Vivo cell tracking, Optical tomography-guided radiation therapy and Ultra-high dose rate irradiation

  • Tao Wang, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Bioinformatics, Biostatistics, Machine learning, Immunogenomics, and Tumor genomics

  • Zhiyue (Jerry) Wang, Ph.D.

    PROFESSOR
    Research Interests: Application of Advanced Neuroimaging Techniques (fMRI, DTI, MRS, etc). Correction of magnetic susceptibility artifacts on brain MRI caused by orthodontic appliances. MR Quality Assurance and Safety. MRI Assessment of Body Iron. Application of AI in medical imaging

  • Guanghua Xiao, Ph.D.

    PROFESSOR
    Research Interests: My methodology research is focused on model development for high-dimensional data such as gene expression, epigenomics, copy number variation, proteomics, genome-wide RNAi functional screening data and brain image data.

  • Yang Xie, Ph.D.

    PROFESSOR
    Research Interests: Biostatistics, bioinformatics, statistical genomics, clinical trial design, and biomarker studies

  • Chao Xing, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests:
    Statistical genetics, genetic epidemiology, bioinformatics, gene mapping for complex traits

  • Vlad Zaha, M.D., Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Detect early changes in the mitochondrial metabolism, in situ, as a marker for asymptomatic, subclinical, doxorubicin induced cardiotoxicity

  • Xiaowei Zhan, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Radiation therapy treatment planning, optimization techniques and algorithms, artificial intelligence technology development and applications

  • Wenhao Zhang, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Computational Neuroscience

  • Jian Zhou, Ph.D.

    ASSISTANT PROFESOR
    Research Interests: Computational Biology; Systems biology and functional Genomics; Machine learning and statistics for biomedical science; Genomic sequence-based regulation

Associate Members

  • Walter Akers, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Biomedical imaging, molecular imaging, optical device design, nanomaterials, cancer biology and treatment

  • Kareem Azab, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Drug Resistance Mechanism, Drug Delivery Systems, Nanoparticles, Immunotherapy, Tissue Engineering

  • Thomas Banks, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Applying new technologies to improve clinical operations, and working in partnership with physicians to develop novel techniques.

  • Dominika Borek, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Eukaryotic chromatin organization, mutational rates and spectra, biological signals and noise

  • Jeffery Cadeddu, M.D.

    PROFESSOR
    Research Interests: Urology; laparoscopy, telesurgical mentoring

  • Murat Cobanoglu, Ph.D.

    UTSW Distinguished Fellow
    Research Interests: Active machine learning driven cancer drug discovery

  • Elizabeth Davenport, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Sub concussive head impact exposure in contact sports, traumatic brain injury, magnetoencephalography

  • Jie Deng, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: MR medical physics, adaptive radiotherapy, imaging, deep learning, MRI, radiology, NMR, pattern recognition, neuroradiology, AI, artificial intelligence, oncology

  • Robert Eberhart, Ph.D.

    PROFESSOR EMERITUS
    Research Interests: Biomaterials; circulatory assist devices

  • Andrew Godley, Ph.D.

    ASSOCIATE PROFESSOR
    DIRECTOR, Clinical Medical Physics

  • Junyo Guo, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Deep learning application in magnetic resonance imaging, dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI)

  • Brian Hrycushko, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Tissue-Response modeling in radiation therapy

  • Mustafa Husain, M.D.

    PROFESSOR
    Research Interests: General psychiatry, aging and geriatric issues, new applications of lead placement in ECT and novel treatments of major depressive disorder including magnetic seizure therapy, transcranial magnetic stimulation, deep brain stimulation, and vagus nerve stimulation

  • Michael Jessen, M.D.

    PROFESSOR & CHAIR
    Research Interests: Circulatory assist devices; cardiac metabolism

  • Romaine Johnson, M.D.

    ASSOCIATE PROFESSOR
    Research Interests: Tissue engineering and regenerative medicine, biomaterials, biomechanics, pediatric airway disorders

  • Julia Kozlitina, Ph.D

    ASSOCIATE PROFESSOR
    Research Interests: Statistics, statistical genetics, genetic epidemiology, genome-wide association studies

  • Jayanthi Lea, M.D.

    PROFESSOR
    Research Interests: Cervical cancer, developmental therapeutics, ovarian cancer, early detection of ovarian cancer

  • Matthew Lewis, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Molecular-imaging instrumentation, linear and nonlinear diffraction tomography, tensor tomography, applied inverse problems

  • Jiaen Liu, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Fast and motion-robust MRI acquisition and reconstruction, High-resolution MRI for in vivo imaging intracortical structure and deep nuclei, Novel MRI contrast and quantification of tissue properties

  • Li Liu, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Molecular Imaging, lung cancer, kidney cancer, tumor microenvironment

  • Robert Mattrey, M.D.

    PROFESSOR
    Director, Ultrasound Research
    Research Interests: Novel molecular-based contrast agents, with emphasis on ultrasound solutions, which can be used to detect and/or treat cancer, including image guided tumor ablation, ultrasound directed drug or gene delivery, or cell-based therapy

  • Roderick McColl, Ph.D.

    PROFESSOR
    Research Interests: fMRI; DICOMs

  • Paul Medin, Ph.D.

    PROFESSOR
    Program Director, Medical Physics Residency
    Research Interests: Tissue-response modeling in radiation therapy; stereotactic radiation therapy

  • Jimin Ren, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: In vivo MRS for studies of energy and phospholipids metabolism in brain and skeletal muscle

  • Scott Smith, Ph.D.

    ASSOCIATE DEAN FOR RESEARCH, PROFESSOR & CHAIR
    Research Interests: Neural cardiovascular control during exercise; reflex dysfunction in heart failure; reflex dysfunction in hypertension

  • Todd Soesbe, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Clinical applications of new spectral CT technologies

  • Durga Udayakumar, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Deciphering molecular characteristics of tumors using Radiogenomics; Identifying quantitative imaging parameters reflective of molecular alterations in solid tumors as noninvasive prognostic and predictive tools; Characterizing biomarkers of bone metastasis

  • Andrew Wang, M.D.

    PROFESSOR
    Associate Vice Chair, Research
    Research Interests: Application of biomedical engineering to cancer research, developing novel cancer diagnostics and therapeutics to improve cancer treatment, genitourinary cancer, gastrointestinal cancers, biomedical engineering, nanotechnology, radiation oncology, translational research, cancer immunotherapy, cancer nanotherapeutics, cancer biomarkers, radioisotopes, nanoparticles, prostate cancer, chemoradiotherapy

  • Tre Welch, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: Biomaterial grafts, coatings and scaffolds; finite element analysis; polymer synthesis; bioresorbable polymer characterization

  • Joel Wells, M.D., M.P.H.

    ASSISTANT PROFESSOR
    Research Interests: Hip dysplasia, femoroacetabular impingement, hip motion, MRI, advanced imaging

  • Yulong Yan, Ph.D.

    ASSOCIATE PROFESSOR
    Director, Computational Physics
    Research Interests: High-performance computing; infrastructure for radiation therapy; radiobiological effects

  • Jaewon Yang, Ph.D.

    ASSISTANT PROFESSOR
    Research Interests: PET, SPECT, Deep Learning

  • Ming Yang, M.D.

    ASSISTANT PROFESSOR
    Research Interests: Adrenal disorders, relationship between obesity and metabolic health and hyposialylation of IgG in adolescent patients

  • Takeshi Yokoo, M.D., Ph.D.

    ASSOCIATE PROFESSOR
    Medical Director, MRI
    Research Interests: Applied mathematics and MRI methods for translational research in liver imaging with special focus on evaluation of nonalcoholic fatty liver disease (NAFLD)

  • Qing Yuan, Ph.D.

    ASSOCIATE PROFESSOR
    Research Interests: Quantitative MRI acquisition and analysis, MRI safety